Cajun Chicken Bites with Cheesy Penne Parmesan Sauce is a delightful dish that brings bold flavors to your table. Perfect for family dinners, gatherings, or a cozy night in, this recipe combines tender chicken bites with a rich, creamy cheese sauce and pasta. The Cajun seasoning adds a spicy kick, making it an exciting meal that everyone will love.
Why You’ll Love This Recipe
- Quick to Prepare: With a cooking time of just 30 minutes, this recipe is perfect for busy weeknights.
- Flavor Explosion: The blend of Cajun spices and creamy cheeses creates a mouthwatering experience.
- Family-Friendly: This dish appeals to all ages, making it great for family meals or entertaining guests.
- Versatile Ingredients: Swap the chicken for turkey or beef if you prefer, and the flavor will still shine.
- Comfort Food at Its Best: Indulge in this creamy pasta dish that warms the soul and satisfies cravings.
Tools and Preparation
To make your cooking experience smooth and enjoyable, gather these essential tools before you begin.
Essential Tools and Equipment
- Large pot
- Skillet
- Mixing bowl
- Whisk
- Measuring cups and spoons
Importance of Each Tool
- Large pot: Essential for boiling pasta efficiently while ensuring even cooking.
- Skillet: Ideal for browning the chicken and creating the delicious cheese sauce in one pan.
- Whisk: Helps combine ingredients smoothly, especially when making sauces.

Ingredients
For the Chicken:
- 1.5 lbs boneless, skinless chicken breasts, cut into bite-sized pieces
- 2 tbsp olive oil
- 1 tbsp Cajun seasoning
- tsp garlic powder
- tsp smoked paprika
- Salt and black pepper, to taste
For the Cheesy Penne:
- 12 oz penne pasta
- 3 tbsp unsalted butter
- 4 cloves garlic, minced
- 2 tbsp all-purpose flour
- 2 cups whole milk
- cup heavy cream
- 1 cups shredded mozzarella cheese
- cup grated Parmesan cheese
- 2 oz cream cheese, softened
- tsp Cajun seasoning (optional, for extra flavor)
- Salt and pepper, to taste
- Chopped parsley, for garnish (optional)
How to Make Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
Step 1: Cook the Penne Pasta
Bring a large pot of salted water to a boil. Add the penne and cook until al dente. Drain and set aside, reserving about cup of pasta water.
Step 2: Season the Chicken
In a bowl, toss the chicken pieces with olive oil, Cajun seasoning, garlic powder, smoked paprika, salt, and pepper until evenly coated.
Step 3: Cook the Chicken
Heat a large skillet over medium-high heat. Add the seasoned chicken and cook for about 6-8 minutes, turning occasionally, until golden brown and fully cooked. Transfer to a plate and keep warm.
Step 4: Make the Sauce
In the same skillet, melt the butter over medium heat. Add the garlic and sauté for 1 minute until fragrant.
Step 5: Create a Roux
Whisk in the flour and cook for 1-2 minutes to form a light roux. Slowly pour in the milk and heavy cream while whisking constantly until smooth. Let it simmer for 3-4 minutes until slightly thickened.
Step 6: Add Cheese
Reduce the heat and stir in the cream cheese until melted. Then add mozzarella, Parmesan, and more Cajun seasoning if desired. Stir until thick, creamy, and cheesy. Season with salt and pepper as needed; thin with reserved pasta water if necessary.
Step 7: Combine Pasta & Chicken
Add cooked penne and chicken bites to the sauce. Stir gently to coat everything in cheesy goodness. Let it warm together for about 1-2 minutes.
Step 8: Serve
Top with fresh parsley if desired, and serve hot! Enjoy your flavorful meal!
How to Serve Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
Serving Cajun Chicken Bites with Cheesy Penne Parmesan Sauce is a delightful way to make your meal memorable. This dish is not only rich and cheesy but also has a spicy kick that elevates the overall experience. Here are some creative serving suggestions to enhance your dining experience.
Plating Suggestions
- Use a large, shallow bowl to showcase the pasta and chicken.
- Garnish with freshly chopped parsley for a pop of color.
Accompaniments
- Pair with crusty garlic bread for a satisfying crunch.
- Serve alongside a fresh garden salad for a refreshing contrast.
Beverage Pairings
- Offer iced tea for a sweet and tangy drink option.
- Lemonade can provide a zesty balance to the dish’s richness.
How to Perfect Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
Perfecting this dish can elevate your cooking skills and impress your guests. Follow these tips to ensure success every time you make it.
- Use fresh ingredients: Fresh herbs and spices enhance flavors significantly.
- Cook pasta al dente: This ensures the pasta holds its shape and texture in the sauce.
- Adjust seasoning: Taste as you go, especially with salt and Cajun seasoning, to suit your preference.
- Keep chicken juicy: Avoid overcooking the chicken by monitoring its internal temperature.
- Garnish generously: Fresh parsley or basil adds color and freshness to each plate.
- Experiment with cheese: Try different types of cheese for unique flavors in your sauce.
Best Side Dishes for Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
Complementing your Cajun Chicken Bites with the right side dishes can elevate the entire meal. Here are some excellent options that work well together.
- Garlic Bread: Crispy on the outside, soft on the inside, perfect for soaking up sauce.
- Caesar Salad: Crisp romaine lettuce paired with creamy dressing balances out the rich pasta.
- Roasted Vegetables: Seasonal vegetables like zucchini and bell peppers add color and nutrients.
- Coleslaw: A crunchy slaw provides a refreshing contrast to the creamy pasta dish.
- Grilled Asparagus: Lightly seasoned asparagus adds elegance and flavor to your meal.
- Corn on the Cob: Sweet corn complements the spicy flavors of Cajun cuisine beautifully.
- Baked Potatoes: Fluffy potatoes offer a comforting side that pairs nicely with cheesy dishes.
- Steamed Broccoli: Bright green broccoli adds nutrition and balances richness in every bite.
Common Mistakes to Avoid
Avoiding common pitfalls can elevate your cooking experience. Here are some mistakes to watch out for:
-
Overcooking the Pasta: Cooking penne pasta too long can make it mushy. Always follow package instructions and aim for al dente.
-
Neglecting Seasoning: Skipping seasoning on the chicken can lead to bland bites. Ensure you coat the chicken thoroughly with spices for full flavor.
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Not Using Enough Fat in the Sauce: A dry sauce can ruin the dish’s creaminess. Use adequate butter and cream to achieve a rich texture.
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Skipping the Cheese Mixing Step: Adding cheese all at once can cause clumping. Mix it gradually into the sauce for a smoother consistency.
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Using Cold Ingredients: Cold cream cheese can be hard to incorporate. Let it soften at room temperature before adding to the sauce for better blending.

Storage & Reheating Instructions
Refrigerator Storage
- Store in an airtight container.
- Keep in the fridge for up to 3 days.
Freezing Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
- Freeze in a freezer-safe container.
- Good for up to 2 months; label with date.
Reheating Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
- Oven: Preheat to 350°F (175°C) and bake for about 20 minutes until heated through.
- Microwave: Heat in short bursts, stirring in between, until warm.
- Stovetop: Warm over low heat, stirring gently to avoid burning.
Frequently Asked Questions
Here are some frequently asked questions about Cajun Chicken Bites with Cheesy Penne Parmesan Sauce:
Can I use different types of pasta?
Yes! Feel free to substitute penne with any pasta shape you prefer, such as fusilli or rotini.
Is this recipe spicy?
The spice level depends on the Cajun seasoning used. Adjust the amount according to your taste preferences.
How can I make this dish healthier?
Consider using whole grain pasta and reducing cheese quantities. You could also add more vegetables like spinach or bell peppers.
What can I serve with Cajun Chicken Bites with Cheesy Penne Parmesan Sauce?
This dish pairs well with a fresh salad or steamed vegetables for a balanced meal.
Can I prepare this dish ahead of time?
Absolutely! You can prepare the chicken and sauce ahead; just combine them right before serving.
Final Thoughts
Cajun Chicken Bites with Cheesy Penne Parmesan Sauce is a delightful fusion of flavors that everyone will love. Its creamy texture and robust seasoning make it perfect for family dinners or casual gatherings. Feel free to customize this dish by adding your favorite vegetables or adjusting the spice levels according to your taste!

Cajun Chicken Bites with Cheesy Penne Parmesan Sauce
- Total Time: 30 minutes
- Yield: Serves approximately 4 people 1x
Description
Enjoy bold flavors with these Cajun Chicken Bites with Cheesy Penne Parmesan Sauce. This quick and easy recipe combines tender chicken bites infused with zesty Cajun spices and enveloped in a rich, creamy cheese sauce over perfectly cooked penne pasta. Ideal for family dinners or cozy nights in, it’s a comforting meal that promises satisfaction for all ages.
Ingredients
- 1.5 lbs boneless, skinless chicken breasts, cut into bite-sized pieces
- 12 oz penne pasta
- 2 tbsp olive oil
- 1 tbsp Cajun seasoning
- tsp garlic powder
- tsp smoked paprika
- Salt and black pepper, to taste
- 3 tbsp unsalted butter
- 4 cloves garlic, minced
- 2 tbsp all-purpose flour
- 2 cups whole milk
- cup heavy cream
- 1 cup shredded mozzarella cheese
- cup grated Parmesan cheese
- 2 oz cream cheese, softened
- tsp Cajun seasoning (optional, for extra flavor)
- Chopped parsley, for garnish (optional)
Instructions
- Cook the penne pasta according to package instructions until al dente, then drain.
- Toss chicken pieces with olive oil and Cajun seasoning. Cook in a skillet over medium-high heat until golden brown (6-8 minutes).
- In the same skillet, melt butter and sauté minced garlic for 1 minute.
- Whisk in flour to create a roux; gradually add milk and heavy cream while stirring until smooth.
- Stir in cream cheese and shredded cheeses until melted and creamy; season as desired.
- Combine cooked chicken and penne with the sauce, stirring gently to coat, then serve hot.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Category: Main
- Method: Skillet
- Cuisine: Cajun
Nutrition
- Serving Size: 1 cup (240g)
- Calories: 540
- Sugar: 5g
- Sodium: 830mg
- Fat: 27g
- Saturated Fat: 15g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 44g
- Fiber: 2g
- Protein: 35g
- Cholesterol: 100mg